Ann Dermatol.  2014 Feb;26(1):119-121. 10.5021/ad.2014.26.1.119.

Epstein-Barr Virus-Positive Primary Cutaneous Diffuse Large B-Cell Lymphoma in an Immunocompetent Patient

Affiliations
  • 1Department of Dermatology, Ajou University School of Medicine, Suwon, Korea. maychan@ajou.ac.kr
  • 2Department of Pathology, Ajou University School of Medicine, Suwon, Korea.

Abstract

No abstract available.


MeSH Terms

B-Lymphocytes*
Humans
Lymphoma, B-Cell*

Figure

  • Fig. 1 Multiple erythematous macules and patches were observed on her trunk (A) and both extremities (B).

  • Fig. 2 (A, B) Skin biopsy revealed multifocal and nodular infiltrates of atypical medium- and large-sized mononuclear cells with enlarged nuclei showing one or more prominent nucleoli (H&E; A: ×40, B: ×400). (C) In situ hybridization for Epstein-Barr virus-encoded RNA was positive in the majority of tumor cells (×200).


Reference

1. Martin B, Whittaker S, Morris S, Robson A. A case of primary cutaneous senile EBV-related diffuse large B-cell lymphoma. Am J Dermatopathol. 2010; 32:190–193.
Article
2. Castillo JJ, Beltran BE, Miranda RN, Paydas S, Winer ES, Butera JN. Epstein-barr virus-positive diffuse large B-cell lymphoma of the elderly: what we know so far. Oncologist. 2011; 16:87–96.
Article
3. Oyama T, Yamamoto K, Asano N, Oshiro A, Suzuki R, Kagami Y, et al. Age-related EBV-associated B-cell lymphoproliferative disorders constitute a distinct clinicopathologic group: a study of 96 patients. Clin Cancer Res. 2007; 13:5124–5132.
Article
4. Park S, Lee J, Ko YH, Han A, Jun HJ, Lee SC, et al. The impact of Epstein-Barr virus status on clinical outcome in diffuse large B-cell lymphoma. Blood. 2007; 110:972–978.
Article
5. Yoshino T, Nakamura S, Matsuno Y, Ochiai A, Yokoi T, Kitadai Y, et al. Epstein-Barr virus involvement is a predictive factor for the resistance to chemoradiotherapy of gastric diffuse large B-cell lymphoma. Cancer Sci. 2006; 97:163–166.
Article
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