Ann Dermatol.  2014 Feb;26(1):26-34. 10.5021/ad.2014.26.1.26.

Epidemiology and Clinical Features of Atopic Dermatitis in Kerman, a Desert Area of Iran

Affiliations
  • 1Department of Pediatric Dermatology, Dermatology and Leishmania Research Center, Kerman University of Medical Sciences, Kerman, Iran. S_farajzadeh@kmu.ac.ir

Abstract

BACKGROUND
Epidemiologic studies of atopic dermatitis (AD) in desert areas are still lacking.
OBJECTIVE
The aim of this study was to investigate the epidemiology of AD in children in Kerman city, a desert area in Iran.
METHODS
We evaluated preschool children (age, 2 to 7 years) and primary school students (age, greater than 7 up to 12 years) in Kerman. We selected 865 students to estimate the prevalence and assess other features of AD such as distribution of lesions, personal history, family history of atopy, aggravating factors, associated symptoms, and morphological variants.
RESULTS
The prevalence of AD was 9.1% in our study population. The prevalence of AD was 9.17% and 9.09% in males and females, respectively. The prevalence of AD in the age range of 2 to 7 years was 13.53% and 8.33% among children aged greater than 7 up to 12 years. In total, 82.27% of the patients were in chronic stage of the disease, and 31.6% had a personal history of other atopic diseases. At least one first-degree family member with atopy was seen in 46.83% of the patients. The most common sites of involvement were the head and neck. The most involved areas in the limbs were extensor surfaces. The most frequent morphological variant of AD was the common type.
CONCLUSION
The prevalence of AD in Kerman was higher than in other Iranian cities but lower than that in developed countries. Diversity in the clinical features of AD has been observed among different studies, and the diagnostic criteria of AD should be adapted in proportion to the studied area.

Keyword

Atopic dermatitis; Epidemiology; Kerman; Preschool and primary school children; Prevalence

MeSH Terms

Child
Child, Preschool
Dermatitis, Atopic*
Developed Countries
Epidemiologic Studies
Epidemiology*
Extremities
Female
Head
Humans
Iran*
Male
Neck
Prevalence

Figure

  • Fig. 1 Data collecting sheet for demographic and clinical features of atopic dermatitis in school and preschool age children in Kerman city.


Reference

1. Williams HC. Epidemiology of atopic dermatitis. Clin Exp Dermatol. 2000; 25:522–529.
Article
2. Friedman PS, Holden CA. Atopic dermatitis. In : Burns T, Breathnach S, Cox N, Griffiths C, editors. Rook's textbook of dermatology. 7th ed. Malden: Blackwell Science;2004. p. 215–230.
3. Nnoruka EN. Current epidemiology of atopic dermatitis in south-eastern Nigeria. Int J Dermatol. 2004; 43:739–744.
Article
4. Tay YK, Kong KH, Khoo L, Goh CL, Giam YC. The prevalence and descriptive epidemiology of atopic dermatitis in Singapore school children. Br J Dermatol. 2002; 146:101–106.
Article
5. Farajzadeh S, Rahnama ZZ, Kamyabi Z, Ghavidel B. Bacterial colonization and antibiotic resistance in children with atopic dermatitis. Dermatol Online J. 2008; 14:21.
Article
6. Farajzadeh S, Behrooz V, Gadari R. The frequency of wart in children with atopic dermatitis and comparison with control group. J Med Sci Islamic Azad University Mashhad. 2008; 3:182–189.
7. Farajzadeh S, Bazargan N, Shahesmaeili A, Shahrbabaki AG, Fekri AR. Evaluation of the frequency of food allergens by skin prick test in children with atopic dermatitis. Iranian J Dermatol. 2010; 13:33–36.
8. Barbaral KIF, Ring J. Clinical features and diagnostic criteria of atopic dermatitis. In : Harper J, Oranje AP, Prose NS, editors. Textbook of pediatric dermatology. 2nd ed. Oxford: Blackwell Publishing;2006. p. 227–258.
9. Wisuthsarewong W, Viravan S. Diagnostic criteria for atopic dermatitis in Thai children. J Med Assoc Thai. 2004; 87:1496–1500.
10. Farajzadeh S, Esfandiarpour I, Poorhamzeh B. Frequency of skin diseases in children in Kerman. Iranian J Dermatol. 2008; 10:44–45.
11. Brenninkmeijer EE, Schram ME, Leeflang MM, Bos JD, Spuls PI. Diagnostic criteria for atopic dermatitis: a systematic review. Br J Dermatol. 2008; 158:754–765.
Article
12. Kang K, Polster AM, Nodorost ST, Steven SR, Cooper KD. Atopic dermatitis. In : Jorizzo JL, Bolognia JL, Schaffer JV, editors. Dermatology. 2nd ed. St. Louis: Mosby/Elsevier;2008. p. 181–195.
13. Olesen AB, Bang K, Juul S, Thestrup-Pedersen K. Stable incidence of atopic dermatitis among children in Denmark during the 1990s. Acta Derm Venereol. 2005; 85:244–247.
Article
14. Laughter D, Istvan JA, Tofte SJ, Hanifin JM. The prevalence of atopic dermatitis in Oregon schoolchildren. J Am Acad Dermatol. 2000; 43:649–655.
Article
15. Afshari F, Khadivi R, Shirzad H. Factors influencing atopic dermatitis in school children of Shahrekord. J Shahrekord Univ Med Sci. 2007; 8:71–78.
16. Moosavi Z, Samadzadeh D. Prevalence of atopic dermatitis in 7-11 year old school children, Ahwaz. J Shahid Sadoughi University Med Sci. 2006; 14:38–44.
17. Benn CS, Melbye M, Wohlfahrt J, Björkstén B, Aaby P. Cohort study of sibling effect, infectious diseases, and risk of atopic dermatitis during first 18 months of life. BMJ. 2004; 328:1223.
Article
18. Bach JF. The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med. 2002; 347:911–920.
Article
19. Mar A, Tam M, Jolley D, Marks R. The cumulative incidence of atopic dermatitis in the first 12 months among Chinese, Vietnamese, and Caucasian infants born in Melbourne, Australia. J Am Acad Dermatol. 1999; 40:597–602.
Article
20. Reidel F. Environmental pollution and atopy. In : Ring J, Przybilla B, Ruzicka T, editors. Handbook of atopic eczema. London: Springer-Verlag;1991.
21. Weiland SK, Hüsing A, Strachan DP, Rzehak P, Pearce N. ISAAC Phase One Study Group. Climate and the prevalence of symptoms of asthma, allergic rhinitis, and atopic eczema in children. Occup Environ Med. 2004; 61:609–615.
Article
22. Semitic [Internet]. The Titi Tudorancea Learning Center;accesed 2010 Oct 3. Available from: http://www.tititudorancea.org/z/semitic.htm.
23. Iranian People & Tribes Monday [Internet]. accesed 2012 Jan 9. Available from: http://www.iranchamber.com/people/articles/iranian_ethnic_groups.php.
24. Centre for Arab genomic studies. Atopic dermatitis [Internet]. Dubai, United Arab Emirates: Centre for Arab Genomic Studies;accessed 2011 Apr 4. Available from: http://www.cags.org.ae.
25. Parthasaradhi A, Al Gufai AF. The pattern of skin diseases in Hail Region, Saudi Arabia. Ann Saudi Med. 1998; 18:558–561.
Article
26. Ansarin H, Firooz A, Azimi M, Ebn-Ahmadi E, Dowlati Y. Prevalence of atopic dermatitis in children in Iran. Gulf Jl Dermatol. 1998; 5:26–27.
27. Malakootian M, Yousefi N. The efficiency of electrocoagulation process using aluminum electrodes in removal of hardness from water. Iranian J Environ Health Sci Eng. 2009; 6:131–136.
28. Lalehzari R, Tabatabaei SH. Groundwater quality mapping in Shahrekord Aquifer. J Environ Stud. 2010; 36:55–62.
29. McNally NJ, Williams HC, Phillips DR, Smallman-Raynor M, Lewis S, Venn A, et al. Atopic eczema and domestic water hardness. Lancet. 1998; 352:527–531.
Article
30. McNally N, Phillips D. Geographical epidemiology of atopic dermatitis. In : Williams HC, editor. Atopic dermatitis: the epidemiology, causes, and prevention of atopic eczema. Cambridge: Cambridge University Press;2000. p. 113–124.
31. Kim CW, Park CJ, Kim JW, Koo DW, Kim KW, Kim TY. Prevalence of atopic dermatitis in Korea. Acta Derm Venereol. 2000; 80:353–356.
Article
32. Sugiura H, Umemoto N, Deguchi H, Murata Y, Tanaka K, Sawai T, et al. Prevalence of childhood and adolescent atopic dermatitis in a Japanese population: comparison with the disease frequency examined 20 years ago. Acta Derm Venereol. 1998; 78:293–294.
Article
33. De D, Kanwar AJ, Handa S. Comparative efficacy of Hanifin and Rajka's criteria and the UK working party's diagnostic criteria in diagnosis of atopic dermatitis in a hospital setting in North India. J Eur Acad Dermatol Venereol. 2006; 20:853–859.
Article
34. Turner JD, Schwartz RA. Atopic dermatitis. A clinical challenge. Acta Dermatovenerol Alp Panonica Adriat. 2006; 15:59–68.
35. Solé D, Camelo-Nunes IC, Wandalsen GF, Mallozi MC, Naspitz CK. Brazilian ISAAC Group. Prevalence of atopic eczema and related symptoms in Brazilian schoolchildren: results from the International Study of Asthma and Allergies in Childhood (ISAAC) phase 3. J Investig Allergol Clin Immunol. 2006; 16:367–376.
36. Böhme M, Svensson A, Kull I, Wahlgren CF. Hanifin's and Rajka's minor criteria for atopic dermatitis: which do 2-year-olds exhibit? J Am Acad Dermatol. 2000; 43:785–792.
Article
37. Kelishadi R, Pour MH, Zadegan NS, Kahbazi M, Sadry G, Amani A, et al. Dietary fat intake and lipid profiles of Iranian adolescents: Isfahan Healthy Heart Program--Heart Health Promotion from Childhood. Prev Med. 2004; 39:760–766.
Article
Full Text Links
  • AD
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr