Korean J Med.
2012 Dec;83(6):706-711.
Role of Chemotherapy in Gastric Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue (MALT) Type
- Affiliations
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- 1Division of Hematology/Oncology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. paark76@hanmail.net
Abstract
- Gastric mucosa-associated lymphoid tissue (MALT) lymphoma comprises approximately 50% of primary gastric lymphoma. Currently, Helicobacter pyroli eradication is the mainstay in the management of localized gastric MALT lymphoma. However, other treatment strategies such as radiotherapy and chemotherapy should be required in certain circumstances which include H. pyroli-negative disease, H. pyroli-positive disease unresponsive to standard eradication, and advanced disease (stage III/IV). Here, we reviewed the role of chemotherapy in the management of patients with gastric MALT lymphoma based on recent clinical trials.
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