Korean J Helicobacter Up Gastrointest Res.  2012 Dec;12(4):265-270. 10.7704/kjhugr.2012.12.4.265.

Two Cases of Gastric MALT Lymphoma Diagnosed at Long Last after Successful Eradication of Helicobacter pylori

• Yeom SJ
• Lee IS
• Cho SG
• Choi MG
• Choi KY
• Park GS

• KMID: 2143415
• DOI: http://doi.org/10.7704/kjhugr.2012.12.4.265

Abstract

The gastric marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) is a rare disease. Helicobacter pylori infection is known as an important etiologic factor of the pathogenesis of MALT lymphoma. H. pylori colonization at the epithelium of gastric mucosa induces T cell and B cell recruitment. T cell induced B cell proliferation develops the MALT in the gastric mucosa. Monoclonal proliferation of B cell in the MALT transform into MALT lymphoma. The eradication of H. pylori is known to induce remission of the disease in more than 80% of patients. But there is no report on progression and development of MALT lymphoma after H. pylori eradication. We experienced two cases of gastric B cell MALT lymphoma diagnosed at long last, after the successful eradication of H. pylori.

Keyword

Helicobacter pylori; MALT lymphoma; Eradication

MeSH Terms

Cell Proliferation
Colon
Epithelium
Gastric Mucosa
Helicobacter
Helicobacter pylori
Humans
Lymphoid Tissue
Lymphoma, B-Cell, Marginal Zone
Rare Diseases