Korean J Med.  2012 Apr;82(4):449-452.

A Case of Duodenal Ulcer Perforation Combined with Scrub Typhus

Affiliations
  • 1Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea. jwoojini@gnah.co.kr

Abstract

Scrub typhus is an acute febrile illness that results from the destruction of endothelial cells by Orientia tsutsugamushi and subsequent systemic vasculitis. It manifests as fever, headache, myalgia, eschar formation, and lymphadenopathy. Some authors have reported that such vasculitis involves the gastrointestinal tract and that hyperemia, erosion, ulceration, and active bleeding of the gastric mucosa subsequently develop. However, no case of ulcer perforation in a patient with scrub typhus has been reported to date. Here, we report the case of a perforated duodenal ulcer in a 70-year-old female patient with scrub typhus.

Keyword

Scrub typhus; Duodenal ulcer; Perforation

MeSH Terms

Aged
Duodenal Ulcer
Endothelial Cells
Female
Fever
Gastric Mucosa
Gastrointestinal Tract
Headache
Hemorrhage
Humans
Hyperemia
Lymphatic Diseases
Orientia tsutsugamushi
Scrub Typhus
Systemic Vasculitis
Ulcer
Vasculitis
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