Korean J Med.  2011 Sep;81(3):387-392.

Natural Course of Benign Pulmonary Metastasizing Leiomyoma

• Park JM
• Choi JS
• Na JO
• Kim YH
• Seo KH
• Oh MH
• Jou SS

Abstract

Benign metastasizing pulmonary leiomyoma is a rare disease that is usually detected several years after hysterectomy or myomectomy. Recently, we experienced two cases, one with monthly chest pain and the other without symptoms, which were diagnosed with benign metastasizing leiomyoma in the lung. A 48-year-old woman who underwent hysterectomy 12 years earlier was referred to us because of multiple pulmonary nodules on chest radiography, and chest pain for 6 months. Thoracoscopic tumor excision was performed. Pathologically, she was diagnosed with benign metastasizing leiomyoma in the lung. After that, chest computed tomography showed tumors with a progressive reduction in size. The other 48-year-old woman, who had undergone myomectomy for uterine leiomyoma 8 years before, visited our hospital for evaluation of incidentally revealed bilateral multiple nodules on chest radiography. The microscopic finding of percutaneous transthoracic needle biopsy revealed a benign pulmonary metastasizing leiomyoma originating from uterine leiomyoma. Multiple nodules on chest radiography were more increased than those performed 1 year and 3 months prior to admission. However, chest X-ray showed tumors that had progressively decreased in size at 6 months after diagnosis of menopause.

Keyword

Leiomyoma; Multiple Pulmonary Nodules; Hysterectomy

MeSH Terms

Biopsy, Needle
Chest Pain
Female
Humans
Hysterectomy
Leiomyoma
Lung
Menopause
Middle Aged
Multiple Pulmonary Nodules
Rare Diseases
Thorax