Korean J Obstet Gynecol.
2001 Oct;44(10):1834-1837.
The causes of primary amenorrhea
- Affiliations
-
- 1Department of Obstetrics and Gynecology, College of Medicine, Seoul National University, Seoul, Korea.
- 2Institute of Reproductive Medicine and Population, Medical Research Center, Seoul National University, Seoul, Korea.
Abstract
OBJECTIVE
To identify the causes of primary amenorrhea in the Korean population.
METHODS
We reviewed the available medical records of the 100 patients who had visited the Department of Obstetrics and Gynecology at Seoul National University Hospital with the complaint of primary amenorrhea and examined their karyotypes between January 1989 and December 2000. Review of history, physical examination, laboratory findings, imaging studies, and operative findings was done, when needed.
RESULTS
The mean age at diagnosis was 25.1+/-6.1 (mean+/-S.D.) years of age, ranged 14 to 40. Mllerian agenesis was the most common cause (40.0%), followed by primary ovarian failure (33.0%), and then followed by hypothalamic-pituitary failure (12.0%). Androgen insensitivity syndrome and Swyer syndrome were found in four patients (4.0%), respectively.
CONCLUSION
This study shows that the common cases of primary amenorrhea in Korean women are Mllerian agenesis, primary ovarian failure and hypothalamic-pituitary failure.
