Korean J Obstet Gynecol.  1999 Feb;42(2):408-411.

Myotonic Dystrophy in Pregnancy complicated with Preterm Labor and Congestive Heart Failure

• Yang SH
• Roh CR
• Chung JH
• Moon ZS
• Moon JT
• Kim BJ

Abstract

Myotonic dystrophy is an autosomal-dominantly inherited neuromuscular disorder characterized by slowly progressive muscular dystrophy, muscle weakness and myotonia. The clinical features may vary from just cataracts to involvement of multiple organ systems such as various muscles, heart, lung and intestine. During pregnancy and delivery, serious maternal and obstetrical complications may occur. The myotonia is often aggravated during pregnancy and it leads to obstetrical complications such as fetal loss, preterm premature delivery, hydrops, in-utero fetal death, difficulties in fetal expulsion, postpartum hemorrhage and/or anesthetic accidents. The affected neonate may display severe hypotonia, facial displegia and respiratory distress. This report presents a woman with myotonic dystrophy complicated with congestive heart failure and preterm delivery during pregnancy.

Keyword

Myotonic dystrophy; Pregnancy; Congestive heart failure; Preterm delivery

MeSH Terms

Cataract
Edema
Estrogens, Conjugated (USP)*
Female
Fetal Death
Heart Failure*
Humans
Infant, Newborn
Intestines
Lung
Muscle Hypotonia
Muscle Weakness
Muscular Dystrophies
Myocardium
Myotonia
Myotonic Dystrophy*
Obstetric Labor, Premature*
Postpartum Hemorrhage
Pregnancy*
Estrogens, Conjugated (USP)