A Case of Late-Onset Adrenal Hyperplasia which Succeeded in Pregnancy

Nam, Y S; Lee, S H; Kwak, I P; Yoon, T K; Cha, K Y

Abstract

Adrenal enzyme deficiencies causing hyperandrogenic symptoms some time after birth have been alternatively called late onset, nonclassical, postpubertal, attenuated, mild, or acquired. Patients previously thought to suffer from the polycystic ovary syndrome (PCOS) and related hyperandrogenic disorders are now being diagnosed as having this genetic disease. By definition, late-onset adrenal hyperplasia is an autosomal recessive disorder causing symptoms in peri-or postpuberty, and all patients demonstrates a normal female external genitalia. We have experienced a case of late-onset adrenal hyperplasia and succeeded in pregnancy. So we report this case with a brief review of literatures.