Korean J Med.  2010 May;78(5):640-644.

A case of primary breast synovial sarcoma diagnosed in a young female patient

Affiliations
  • 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. moisa@snu.ac.kr
  • 2Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.
  • 3Department of Thoracic and Cardiovascular Surgery, Seoul National University College of Medicine, Seoul, Korea.
  • 4Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.

Abstract

Synovial sarcoma is a malignant soft tissue neoplasm that develops mainly in para-articular locations in the extremities, but can arise in a wide variety of other sites. Primary breast synovial sarcoma has been reported infrequently worldwide. We report the case of 15-year-old female who was diagnosed with primary breast synovial sarcoma. We performed wide excision for the breast mass. However, local recurrence was detected 9 months later. We performed wide excision for the recurrent breast tumor. After 27 months, a solitary metastasis was found in the right upper lobe of the lung. We performed wedge resection for the lung mass and treated her with palliative chemotherapy using doxorubicin and ifosfamide. Twenty-eight months after chemotherapy, she is alive without evidence of recurrence. We report the details of this case along with a review of the literature.

Keyword

Synovial sarcoma; Breast; Surgery; Chemotherapy

MeSH Terms

Adolescent
Breast
Breast Neoplasms
Doxorubicin
Extremities
Female
Humans
Ifosfamide
Lung
Neoplasm Metastasis
Recurrence
Sarcoma, Synovial
Soft Tissue Neoplasms
Doxorubicin
Ifosfamide
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