Korean J Med.  2010 Dec;79(6):714-719.

Neurolymphomatosis in a patient with T-cell non-Hodgkin's lymphoma

Affiliations
  • 1Department of Internal Medicine, Daejeon St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea. parkjichan@hanmail.net
  • 2Department of Diagnostic Radiology, Daejeon St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.

Abstract

Neurolymphomatosis, defined as a selective infiltration of lymphoma cells into cranial nerves, peripheral nerves and nerve roots, is a rarely recognized manifestation of lymphoma. Its characteristic symptoms are often overlooked or mistaken for other conditions, such as a peripheral polyneuropathy, due to chemotherapeutic agents or clinical findings of metastatic lesions in the central nervous system. Recently, neurolymphomatosis has been increasingly recognized using magnetic resonance imaging and positron emission tomography-computed tomography. We present a case of neurolymphomatosis manifesting as peripheral mononeuropathy in a patient with T-cell non-Hodgkin's lymphoma.

Keyword

Neurolymphomatosis; Lymphoma

MeSH Terms

Animals
Central Nervous System
Cranial Nerves
Electrons
Humans
Lymphoma
Lymphoma, Non-Hodgkin
Magnetic Resonance Imaging
Marek Disease
Mononeuropathies
Peripheral Nerves
Polyneuropathies
T-Lymphocytes
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