Korean J Med.  2008 Jul;75(1):108-111.

A case of myocardial infarction with antiphospholipid syndrome

• Choi HS
• Kim ES
• Min JY
• Kang KM
• Kim JH
• Yoo KD
• Kim CM

Abstract

Antiphospholipid syndrome is a multi-system disorder characterized by arterial or venous thromboses and antiphospholipid antibodies, such as lupus anticoagulant or anticardiolipin antibodies. Most common clinical manifestations are recurrent pregnancy losses and deep vein thromboses. Cardiac manifestations in antiphospholipid syndrome include valve abnormalities, occlusive arterial disease, intracardiac emboli, and ventricular dysfunction. Acute myocardial infarction is a rare manifestation of the primary antiphospholipid syndrome. We have experienced a case of myocardial infarction with antiphospholipid syndrome. A 35-year-old man with no cardiovascular risk factors, other than smoking, presented with chest pain. He was diagnosed with an acute myocardial infarction. Our evaluation for coagulapathy revealed elevated lupus anticoagulant antibody. The antiphospholipid syndrome should be considered early in the differential diagnosis as an important cause of unexplained thrombosis in young patients.

Keyword

Antiphospholipid syndrome; Myocardial infarction; Lupus anticoagulant

MeSH Terms

Adult
Antibodies, Anticardiolipin
Antibodies, Antiphospholipid
Antiphospholipid Syndrome
Chest Pain
Diagnosis, Differential
Humans
Lupus Coagulation Inhibitor
Myocardial Infarction
Pregnancy
Risk Factors
Smoke
Smoking
Thrombosis
Venous Thrombosis
Ventricular Dysfunction
Antibodies, Anticardiolipin
Antibodies, Antiphospholipid
Lupus Coagulation Inhibitor
Smoke