Korean J Neurogastroenterol Motil.  2006 Jun;12(1):77-80.

A Case of Barrett's Esophagus Developed 1 Year after Subtotal Gastrectomy due to Stomach Cancer

• Kwon HC
• Lee KJ
• Kim JH
• Yoo JH
• Choi JM
• Sin SJ
• Chung JY
• Hahm KB
• Kim JH
• Cho SW

Abstract

Barrett's esophagus is characterized by replacement of esophageal squamous epithelium with specialized intestinal metaplasia as a consequence of long standing gastro-esophageal reflux. It is a major risk factor for esophageal adenocarcinoma. With regard to the pathogenesis of Barrett's esophagus other than acid reflux, hiatal hernia and duodenogastroesophageal bile reflux are implicated. According to several previous reports, acid reflux associated with bile reflux has been suggested to be a major risk factor for Barrett's esophagus. This case study reports a patient with Barrett's esophagus which developed one year after subtotal gastrectomy with gastroduodenostomy due to gastric cancer. Before the operation, the patient had a hiatal hernia but no Barrett's esophagus. This case represents a significant model for the development of Barrett's esophagus when acid reflux is combined with duodenogastroesophageal bile reflux.

Keyword

Barrett's esophagus; Bile reflux; Hiatal hernia; Subtotal gastrectomy

MeSH Terms

Adenocarcinoma
Barrett Esophagus*
Bile Reflux
Epithelium
Gastrectomy*
Gastroesophageal Reflux
Hernia, Hiatal
Humans
Metaplasia
Risk Factors
Stomach Neoplasms*
Stomach*