Korean J Nephrol.  1997 Dec;16(4):809-813.

A Case of Acute Pancreatitis as a Complication of Systemic Lupus Erythematosus

• Shin GT
• Ma KA
• Han DS
• Jung HJ
• Yim HE
• Kim HS
• Kim DH

Abstract

Systemic lupus erythematosus(SLE) is a multisystem disease. Gastrointestinal manifestations are common in SLE, occurring in 35% to 40% of patients at some stage of their illness. Acute pancreatitis is a rare complication of SLE. To date, seventy cases of acute pancreatitis related to SLE have been reported and fourteen cases were unrelated to drugs such as steroids, diuretics or other immunosuppressive agents. Furthermore, only seven out of fourteen cases manifested acute pancreatitis in their initial course of SLE as was seen in our case. Additionally, there have been no such cases reported in Korea. Corticosteroids have been considered as both a cause and as a therapy for acute pancreatitis. We report a case of acute pancreatitis in a 40 year old Korean man presenting with multi-organ manifestations and diagnosed to have SLE. Renal biopsy showed membranous glomerulonephritis(WHO Class V). His serum amylase and lipase returned to normal on high dose prednisolone treatment.

Keyword

Systemic lupus erythematosus; Acute pancreatitis; Corticosteroids

MeSH Terms

Adrenal Cortex Hormones
Adult
Amylases
Biopsy
Diuretics
Humans
Immunosuppressive Agents
Korea
Lipase
Lupus Erythematosus, Systemic*
Pancreatitis*
Prednisolone
Steroids
Adrenal Cortex Hormones
Amylases
Diuretics
Immunosuppressive Agents
Lipase
Prednisolone
Steroids