Korean J Nephrol.  1998 Jul;17(4):644-648.

A Case of Acute Renal Failure and Other Symptoms Associated with Phytolacca Radix Poisoning

Abstract

Phytolaccae had been used as a pharmaceutical drug or food But nowadays, due to its toxicity, Phytolaccae is rarely used and cases of patients poisoned with it are seldom reported. The case presented here was of 43 year-old male who after ingesting extract of Phytolacca esculenta suffered from abdominal pain, diarrhea, nausea, vomiting, tachycardia, hypotension, pruritus, paresthesia, oliguria and azotemia. Kidney biopsy revealed tubular necrosis and some protein casts in tubular lumens. These findings suggested that acute renal failure was mainly caused by nephrotoxicity of Phytolacca extracts. Through continuous arteriovenous hemofiltration and two times of hemodialysis, he was completely recovered from acute renal failure. Other symptoms also disappeared by symptomatic management, but paresthesia of both lower extremities still remained. So we reported this case with a brief review of literature.

Keyword

Phytolaccae; Acute renal failure; Acute tubular necrosis; Poisoning

MeSH Terms

Abdominal Pain
Acute Kidney Injury*
Adult
Azotemia
Biopsy
Diarrhea
Hemofiltration
Humans
Hypotension
Kidney
Lower Extremity
Male
Nausea
Necrosis
Oliguria
Paresthesia
Phytolacca*
Poisoning*
Pruritus
Renal Dialysis
Tachycardia
Vomiting
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