Korean J Nephrol.
2002 May;21(3):469-474.
A Case of Type 1 Renal Tubular Acidosis Accompanying Renal Stone and Nephrocalcinosis Caused by Hypocitraturia
- Affiliations
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- 1Department of Internal Medicine, Medical College, The Catholic University of Korea, Seoul, Korea. ysc543@unitel.co.kr
Abstract
- Renal stone and nephrocalcinosis are common clinical manifestations of type 1 renal tubular acidosis. In normal state, citrate plays the most critical role in suppressing stone formation as it combines with calcium. In type 1 RTA, increased reabsorption of citrate in proximal tubule results in low citrate excretion, which precipitates renal stone formation. We report a case of type 1 RTA accompanying renal stone and nephrocalcinosis caused by hypocitraturia. A 16-year-old male patient who had renal stone and nephrocalcinosis showed hypocitraturia. Incomplete type 1 RTA was proved as the cause of hypocitraturia by bicarbonate and ammonium loading test in the patient.
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