J Korean Pediatr Soc.
1980 Apr;23(4):321-325.
A Case of Nephrotic Syndrome Associated with Distal Type Tubular Acidosis, Nephrocalcinosis and Renal Osteodystrophy
- Affiliations
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- 1Department of Pediatrics, College of Medicine Yonsei University, Seoul, Korea.
- 2Department of Pathology, College of Medicine Yonsei University, Seoul, Korea.
Abstract
- A non-familial type nephrotic syndrome associated with distal renal tubual acidosis, nephrocalcinosis and renal osteodystropy is a very rare disease. A 4 year old boy was treated with prednisone under the impression of minimal lesion nephrotid syndrome but the response was not excellent along with persistant microhematuria in his serial urinalysis. Percutaneous renal biopsy speciman revealed microcalcification around afferent arteriols and peritubular area along with mild mesangial cell proliferations. Futher studies disclosed osteodystrophic change of the femurs. Patient had a typical forms of distal type renal tubular acidosis which was confirmed by NH4Cl and NaHCO3 loading tests. This case is the first cases of non-familial type nephrotic syndrome associated with nephrocalcinosis, renal osteodystrophy and distal RTA in Korea.
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