Korean J Med.  2002 Sep;63(3):251-260.

The clinical effects of the BiodivYsio Phosphorylcholine-coated Stent in patients with small coronary artery diseases

• Hong YJ
• Jeong MH
• Shim DS
• Lim SY
• Yang BR
• Lee SH
• Lee SH
• Park OY
• Park WS
• Kim JH
• Choi MJ
• Kim IS
• Kim W
• Ahn YK
• Cho JG
• Park JC
• Kang JC

Abstract

BACKGROUND: The BiodivYsio stent is a balloon-expandable stent coated with phosphorylcholine designed to reduce the formation of thrombus and the risk of restenosis.
METHODS
We prospectively studied 20 patients who underwent implantation of BiodivYsio stent (group I; 60.8+/-9.3 years, male 60.0%) and compared to 20 patients who underwent balloon angioplasty alone (group II; 60.3+/-7.9 years, male 45.0%) for small coronary arterial lesions (target arterial diameter was between 2.0 mm and 2.8 mm) between February 2001 and October 2001. Major adverse cardiac events such as acute myocardial infarction, target vessel revascularization and death were evaluated during hospital admission and at 6-months after percutaneous coronary intervention (PCI).
RESULTS
During hospitalization, the incidence of acute myocardial infarction, target vessel revascularization and death was not different between the two groups. At follow-up coronary angiography 6 months after PCI, the incidence of restenosis was lower in group I than in group II (Group I; 3/20, 15.0% vs Group II; 9/20, 45.0%, p=0.032) and the incidence of target vessel revascularization (TLR) was lower in group I than in group II (Group I; 3/20, 15.0% vs Group II; 8/20, 40.0%, p=0.041).
CONCLUSION
Coronary BiodivYsio stenting in small coronary artery leads to excellent short- and mid-term clinical outcomes.

Keyword

Coronary artery diseases; Percutaneous coronary intervention; Restenosis; Balloon; Stents

MeSH Terms

Angioplasty, Balloon
Coronary Angiography
Coronary Artery Disease*
Coronary Vessels*
Follow-Up Studies
Hospitalization
Humans
Incidence
Male
Myocardial Infarction
Percutaneous Coronary Intervention
Phosphorylcholine
Prospective Studies
Stents*
Thrombosis
Phosphorylcholine