Korean J Hematol.
2003 Aug;38(3):188-190.
A Case of Anaphylactic Response to Factor lX Replacement Therapy in Hemophilia B Patient
- Affiliations
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- 1Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea. hahnglee@email.hanyang.ac.kr
Abstract
- We report a first korean case of anaphylactic response to factor lX replacement therapy in 22-month-old male hemophilia B patient. He was admitted to our hospital via emergency room due to anaphylactic response after factor lX infusion. Immediately after the infusion, he became dyspneic and cyanotic. The symptoms completely resolved after sleep. He represented same symptoms after next factor lX infusion, which completely resolved by the administration of oxygen. At the time of anaphylaxis, inhibitors of factor lX was demonstrated(8.8 Bethesda Unit). We planned him to treat with recombinant factor Vll or diluted factor lX at bleeding episode.
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