Korean J Dermatol.
2001 Sep;39(9):1027-1030.
Botulinum Toxin Treatment in a Patient with Frey Syndrome After Upper Thoracic Sympathicotomy
- Affiliations
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- 1Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea. hceun@snu.ac.kr
- 2Department of National Cancer Center, Seoul National University College of Medicine, Seoul, Korea.
- 3Dream Dermatology, Seoul, Korea.
- 4Laser Center, Seoul, Korea.
Abstract
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Frey syndrome is characterized by profuse facial sweating which is provoked by the taste of food. It has been described as a consequence of upper thoracic sympathicotomy. Botulinum toxin injection is a relatively new treatment modality for Frey syndrome. Botulinum toxin type A (Botox , Allergan, USA) had been successfully used to treat Frey syndrome occurring in a 38-year-old patient following thoracic sympathicotomy for palmar hyperhidrosis. A total dose of 100U of botulinum toxin (1.0U/0.1ml/cm2) injection resulted in a 6 months' resolution of sweating, burning, and flushing sensation on eating. During the follow-up period, no systemic side effects were experienced.