Korean J Dermatol.  2001 Sep;39(9):995-999.

A Case of Churg-Strauss Syndrome With Acute Glomerulonephritis

• Park HY
• Park TH
• Jeong MC
• Yoo JH
• Kim KJ
• Lee KB

Abstract

Churg-Strauss syndrome is a rare systemic vasculitis diagnosed by the presence of any four or more of six criteria which include asthma, eosinophilia>10%, mono- or poly-neuropathy, nonfixed pulmonary infiltrate, paranasal sinus abnormality, extravascular eosinophils. In a 65 year-old-woman, multiple purpura and crusted ulcer with central necrosis were developed on the both extremities and buttocks 1 month ago. She has been suffered from asthma, sinusitis and recurrent pneumonia since ten years ago Laboratory findings showed hematuria, hypereosinophilia and hyperIgE. On the histological examination of ulcerative nodule on the right leg, leukocytoclastic vasculitis and many neutrophils and eosinophils around the cutaneous vessels were seen and the other findings were fibrinoid necrosis and thickening of vessels wall without eosinophilic granulomatous changes. Renal biopsy showed focal segmental glomerulonephritis and sclerosing nephritis. We report a rare case of Churg-Strauss syndrome with acute glomerulonephritis.

Keyword

Churg-strauss syndrome; glomerulonephritis

MeSH Terms

Asthma
Biopsy
Buttocks
Churg-Strauss Syndrome*
Eosinophils
Extremities
Glomerulonephritis*
Hematuria
Leg
Necrosis
Nephritis
Neutrophils
Pneumonia
Purpura
Sinusitis
Systemic Vasculitis
Ulcer
Vasculitis