Endoscopic Finding According to Symptoms in Patients with Functional Dyspepsia

Kim, Jin Il; Jun, Eun Jung; Kim, Tae Ho; Kim, Jeong Ho; Cheung, Dae Young; Chung, Woo Chul; Kim, Byung Wook; Kim, Sung Soo; Park, Soo Heon

Abstract

BACKGROUND/AIMS
This study verifies whether endoscopic findings differ according to the symptoms of patients with functional dyspepsia.
MATERIALS AND METHODS
This study surveyed upper gastrointestinal symptoms in 325 patients with functional dyspepsia and conducted esophagogastroduodenoscopy. The endoscopic findings were classified according to the Sydney classification, as edema, erythema, friability, exudates, flat erosion, raised erosion, rugal hyperplasia, atrophy, visibility of vascular pattern, intramural bleeding spot, nodularity, respectively in antrum, body and fundus.
RESULTS
1) The average age of 325 patients was 47.8 years. There were 134 males and 191 females among the 325 patients. 2) Among 325 patients, 134 (41.2%) had epigastric pain syndrome, 169 (52.0%) had postprandial distress syndrome, and 22 (6.7%) had unspecific dyspepsia. 3) Compared to postprandial distress syndrome patients, those with epigastric pain syndrome had more erythema (85.1% vs. 60.2%, P<0.01) and raised erosion (26.0% vs. 18.9%, P=0.01) in antrum, and more erythema (59.0% vs. 36.7%, P=0.02) in body. 4) Compared to epigastric pain syndrome patients, those with postprandial distress syndrome had more atrophy (23.7% vs. 10.4%, P=0.04) in fundus.
CONCLUSIONS
Erythma and raised erosion were more frequently observed in antrum of epigastric pain syndrome patients, and atrophy was frequently observed in fundus of postprandial distress syndrome patients, through endoscopy.