Korean J Dermatol.  2005 Oct;43(10):1423-1425.

A Case of Acneiform Eruption Occurring after Injection of Cetuximab (Erbitux(R), IMC-C225)

Affiliations
  • 1Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. dylee@smc.samsung.co.kr

Abstract

We report a case of acneiform skin eruption induced by cetuximab in a 58-year-old man. Cetuximab is a new anticancer agent, which acts as a selective epidermal growth factor receptor monoclonal antibody. Our patient had taken cetuximab for the treatment of metastatic rectal cancer and visited our clinic with multiple erythematous papules and pustules on the face, postauricular area and anterior chest. A skin biopsy from his forehead revealed destruction of the follicular structure and perifollicular inflammatory cellular infiltrations composed of neutrophils and lymphocytes.

Keyword

Cetuximab; Acneiform eruption

MeSH Terms

Acneiform Eruptions*
Biopsy
Forehead
Humans
Lymphocytes
Middle Aged
Neutrophils
Receptor, Epidermal Growth Factor
Rectal Neoplasms
Skin
Thorax
Cetuximab
Receptor, Epidermal Growth Factor
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