Korean J Dermatol.
2006 May;44(5):620-623.
A Case of Anticonvulsant Hypersensitivity Syndrome thought to be Caused by Lamotrigine
- Affiliations
-
- 1Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea. kwanglee@yumc.yonsei.ac.kr
- 2Department of Dermatology, Ajou University College of Medicine, Suwon, Korea.
Abstract
- Anticonvulsant hypersensitivity syndrome (AHS) is a rare and potentially life-threatening drug reaction, which has been associated with aromatic anticonvulsants such as phenytoin, carbamazepine, and phenobarbital. It is characterized by the triad of fever, rash and internal organ involvement, which mostly includes hepatitis. Histopathological findings usually show characteristic erythema multiforme. Lamotrigine is a new antiepileptic drug, chemically distinct from other anticonvulsant medication, however, AHS has recently been documented in patients treated with lamotrigine. We report a case of AHS in a 29-year-old man, thought to have been caused by the use of lamotrigine.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Three Cases of Anticonvulsant Hypersensitivity Syndrome Associated with Lamotrigine
- Lamotrigine-induced Anticonvulsant Hypersensitivity Syndrome: Treatment with Steroid and Intravenous Immunoglobulin
- DRESS (drug reaction with eosinophilia and systemic symptoms) syndrome induced by lamotrigine in a child
- A Case of Anticonvulsant Hypersensitivity Syndrome Induced by Carbamazepine
- Hypersensitivity Reaction in a Patient Treated with Lamotrigine and Aripiprazole: a Case Report
