Korean J Dermatol.  2006 Dec;44(12):1454-1456.

A Case of Cutaneous Metastasis from Suspected Transitional Cell Carcinoma of the Renal Pelvis

• Kim YY
• Kim MY
• Park YM
• Kim HO

Abstract

Transitional cell carcinoma (TCC) of the renal pelvis is a rare cancer, and moreover, cutaneous metastasis of this cancer is extremely rare. Herein we report a case of cutaneous metastasis from suspected TCC of the renal pelvis, which first manifested itself as an internal malignancy. A 60-year-old man presented with four bean-sized, skincolored, subcutaneous nodules on the left-hand side of his neck and flank. The mass had infiltrated into the surrounding fat tissue, and consisted of 3~5 layers of tumor cells of various sizes with nuclear enlargement and prominent nucleoli. Immunohistochemical staining with CK 7, CK 20 and alpha-methylacyl CoA racemase were strongly positive, partially positive and negative, respectively. These histopathologic findings were consistent with a high grade TCC. The patient was suspected of having TCC of the renal pelvis with extensive metastases. Biopsy of the mass in the renal pelvis was planned, yet unfortunately the patient died before this was carried out.

Keyword

Cutaneous metastasis; Transitional cell carcinoma of the renal pelvis

MeSH Terms

Biopsy
Carcinoma, Transitional Cell*
Humans
Kidney Pelvis*
Middle Aged
Neck
Neoplasm Metastasis*