Korean J Dermatol.  2014 Feb;52(2):120-123.

Cutaneous Metastasis of Transitional Cell Carcinoma of the Renal Pelvis, Clinically Mimicking an Abscess

• Lee JH
• Kim JE
• Kang H

Abstract

Upper tract urothelial carcinoma (UTUC), which comprises tumors of the ureter and renal pelvis, is a rare genitourinary malignancy. Among these tumors, transitional cell carcinoma (TCC) of the renal pelvis is highly uncommon, and cutaneous metastasis of this tumor is very rare. Herein, we report a case of cutaneous metastasis of TCC of the renal pelvis, clinically mimicking an abscess. A 79-year-old woman was diagnosed with TCC of the left renal pelvis, and underwent wide nephrectomy and chemotherapy in August 2012. She presented with painful, solitary 3 cm sized erythematous dome-shaped mass on the right lower abdomen that had been present for two weeks. We took biopsies of the center and periphery of the mass. Histopathological findings were consistent with cutaneous metastasis of TCC. Immunohistochemical examination showed strongly positive cytokeratin 7 staining, and negative cytokeratin 20 and thrombomodulin staining.

Keyword

Abscess; Cutaneous metastasis; Renal pelvis; Transitional cell carcinoma

MeSH Terms

Abdomen
Abscess*
Aged
Biopsy
Carcinoma, Transitional Cell*
Drug Therapy
Female
Humans
Keratin-20
Keratin-7
Kidney Pelvis*
Neoplasm Metastasis*
Nephrectomy
Thrombomodulin
Ureter
Keratin-20
Keratin-7
Thrombomodulin