Korean J Infect Dis.  1999 Apr;31(2):136-140.

The Effects of Inline Intravenous Filtration on Bacteria, Candida and Bacterial Endotoxin Retentions

Affiliations
  • 1Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
  • 2Department of Clinical Pathology, Korea University College of Medicine, Seoul, Korea.

Abstract

BACKGROUND: In-line intravenous filters have been used in intravenous administration sets of fluid to retain bacteria and bacterial endotoxin. We evaluated the effects of intravenous filters on Staphylococcus epidermidis, Pseudomonas aeruginosa, Candida and bacterial endotoxin retention.
METHODS
S. epidermidis, C. albicans, P. aeruginosa and endotoxin were injected into each 10 bags of amino acid solution. After incubation for 24 and 72 hours, aspirates of 0.1 mL from 30 bags, with filtration and without filtration, were inoculated into culture media. The effluent from bags containing endotoxin was tested by limulus amebocyte lysate test.
RESULTS
When effluents were filtered before culture, those from each 10 bags containing P. aeruginosa, C. albicans and endotoxin were sterile; also there was only one positive bacterial culture among 10 effluents from bags containing S. epidermidis. But by contrast all effluents without filtration showed positive cultures and endotoxin detection.
CONCLUSION
This result showed that inline intravenous filters were useful device to remove bacteria, Candida, and bacterial endotoxin.

Keyword

Intravenous filter; Bacteria; Endotoxin

MeSH Terms

Administration, Intravenous
Bacteria*
Candida*
Culture Media
Filtration*
Horseshoe Crabs
Pseudomonas aeruginosa
Staphylococcus epidermidis
Culture Media
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