Korean J Infect Dis.
2000 Oct;32(5):402-406.
A Case of Syphilitic Aortitis with Aortic Insufficiency and Aortic
Aneurysm
Abstract
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Syphilitic aortitis, passing out of our mind, is the most common systemic manifestation of
late syphilis and is more typically manifestated 10 to 30 years afterward. This diagnosis
has been made less frequently in recent decades than in the past, because of public awareness
of syphilis and screening program. Treponema pallidum lodge within vasa vasorum, especially
ascending aorta cause the histologic changes, which are responsible for the three major forms
of symptomatic cardiovascular syphilis, including aortic insufficiency, coronary ostial
stenosis, and aortic aneurysm. We experienced a case of syphilitic aortitis with aortic
insufficiency and aortic aneurysm in a 48-year-old man presented with progressive dyspnea.
Echocardiography, chest CT, and later surgical correction were performed and surgical
specimen revealed the histologic finding consistent with syphilitic aortitis. We report
this case with a review of the literature.