Korean J Dermatol.  2008 May;46(5):674-677.

A Case of Pancreatic Panniculitis

Affiliations
  • 1Department of Dermatology, Chonbuk National University Medical School, Jeonju, Korea. dermayun@chonbuk.ac.kr

Abstract

We report a case of pancreatic panniculitis associated with acute pancreatitis. The patient was a 63-year-old woman who presented with multiple painful erythematous nodules on both shins and had a mild fever and chill. Histopathologic findings showed fat necrosis with anucleate "ghost-like" fat cells with a thick shadowy wall. Laboratory evaluation revealed an increase in serum blood amylase and lipase. We diagnosed as pancreatic panniculitis associated with acute pancreatitis. Past medical history included rheumatoid arthritis and chronic renal failure treated with hemodialysis. She was taking several medicines due to rheumatoid arthritis and was newly prescribed the mizoribine (Bredinin(R)), 50 mg twice daily for 50 days. We therefore considered the possibility of drug induced pancreatitis due to mizoribine.

Keyword

Pancreatic panniculitis

MeSH Terms

Adipocytes
Amylases
Arthritis, Rheumatoid
Fat Necrosis
Female
Fever
Humans
Kidney Failure, Chronic
Lipase
Middle Aged
Pancreatitis
Panniculitis
Renal Dialysis
Ribonucleosides
Amylases
Lipase
Ribonucleosides
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