Korean J Dermatol.  2009 Sep;47(9):1090-1093.

Successful Treatment of Localized Epidermolysis Bullosa Acquisita with Low-dose Dapsone and Topical Tacrolimus

Affiliations
  • 1Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.

Abstract

A 52-year-old man had a twenty-five year history of recurrent bullous eruption that was localized to both cheeks. The diagnosis of epidermolysis bullosa acquisita was confirmed by means of direct immunofluorescence and salt-split direct immunofluorescence studies that were performed on the perilesional skin. The patient has been in partial remission state with the treatment of low dose dapsone (12.5~25 mg) and topical tacrolimus. Herein, we report on a case of EBA localized to the face, and it showed a favorable response to treatment with low-dose dapsone and topical tacrolimus.

Keyword

Dapsone; Localized epidermolysis bullosa acquisita; Tacrolimus

MeSH Terms

Cheek
Dapsone
Epidermolysis Bullosa
Epidermolysis Bullosa Acquisita
Fluorescent Antibody Technique, Direct
Humans
Middle Aged
Skin
Tacrolimus
Dapsone
Tacrolimus
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