Korean J Dermatol.  2011 Sep;49(9):837-839.

Childhood Granulomatous Periorificial Dermatitis Treated with Topical Tacrolimus

Affiliations
  • 1Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea. drseo@hanafos.co.kr

Abstract

Childhood granulomatous periorificial dermatitis (CGPD) is a benign facial eruption of unknown etiology characterized by a monomorphic papular eruption occurring in the perinasal, perioral, and periocular areas. We report an 11-year-old boy with characteristic features of CGPD. He presented with a 4-month history of non-pruritic, papular eruptions on the face. The histopathologic exam revealed an upper dermal granuloma with surrounding lymphocytes. Treatment was initiated with tetracycline 500 mg/day, but there was no response for 3 weeks. We tried 0.03% topical tacrolimus to treat recalcitrant skin lesions. After 10 weeks of treatment, the lesions resolved without scarring.

Keyword

Childhood granulomatous periorificial dermatitis; Tacrolimus

MeSH Terms

Child
Cicatrix
Dermatitis
Granuloma
Humans
Lymphocytes
Skin
Tacrolimus
Tetracycline
Tacrolimus
Tetracycline
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