Korean J Dermatol.  2011 Nov;49(11):1002-1005.

Childhood Granulomatous Periorificial Dermatitis Improved by Dapsone

• Lee MW
• Park HC
• Lee JW
• Yu HJ
• Kim JS

Abstract

Childhood granulomatous periorificial dermatitis is a distinctive granulomatous form of perioral dermatitis, characterized by a monomorphous, small papular eruption around the mouth, nose, and eyes. It occurs primarily in prepubertal children. We present a case of a 12-year-old boy with multiple, asymptomatic, erythematous papules on the perioral, perinasal and periorbital areas for 5 months. Histopathological examination revealed upper dermal and perifollicular granulomatous infiltrate. After using oral dapsone 25 mg daily for 7 weeks, the skin lesions were considerably improved. But, 3 months after discontinuence of dapsone, exacerbation of the skin lesions occurred.

Keyword

Childhood granulomatous periorificial dermatitis; Dapsone

MeSH Terms

Child
Dapsone
Dermatitis
Dermatitis, Perioral
Eye
Humans
Mouth
Nose
Skin
Dapsone