Korean J Dermatol.  2012 Sep;50(9):830-833.

Vitiligo Developed in a Patient with Discoid Lupus Erythematosus

• Jeon SY
• Hong JW
• Song KH
• Kim KH

Abstract

Vitiligo has been associated with various disorders, including pernicious anemia, diabetes, hyperthyroidism, alopecia areata, and Addison's disease. Discoid lupus erythematosus (DLE), the most common form of chronic cutaneous lupus erythematosus, is an autoimmune disease characterized by skin involvement. A 64-year-old man presented with multiple DLE lesions on the face and the neck, as well as photosensitive eczema on the nape of the neck. After treatment, the DLE lesions improved, but poliosis and several depigmented patches appeared on the vertex, the nape of the neck, and on the right hand. Few reports are available about the concurrence of DLE and vitiligo in other countries, and only one case, which showed coexisting systemic lupus erythematosus and vitiligo, has been reported in the Korean literature. The pathogenesis of concurrence of these two diseases has not been fully elucidated. Herein, we present a case of vitiligo that developed in a patient with DLE.

Keyword

Discoid lupus erythematosus; Vitiligo

MeSH Terms

Addison Disease
Alopecia Areata
Anemia, Pernicious
Autoimmune Diseases
Eczema
Hand
Humans
Hyperthyroidism
Lupus Erythematosus, Cutaneous
Lupus Erythematosus, Discoid
Lupus Erythematosus, Systemic
Middle Aged
Neck
Skin
Vitiligo