Korean J Dermatol.  2013 Sep;51(9):743-745.

A Case of Psoriasiform Dermatitis Following Adalimumab Injection for Treatment of Ankylosing Spondylitis

Affiliations
  • 1Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea. 20100112@kuh.ac.kr

Abstract

Adalimumab (Humira(TM)) is the first fully humanized monoclonal TNF-alpha antibody that antagonizes the effects of TNF-alpha. Its use has been found in the treatment of various rheumatologic disorders, namely rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis, as well as for various skin conditions such as psoriasis. As the use of this particular biologic agent is becoming more widespread, cutaneous adverse effects of the drug is now being reported at a steady rate. The authors herein report a case of 32 year-old female who presented with multiple psoriasiform eruptions on her trunk, back and lower extremities. She had a four-year history of ankylosing spondylitis, for which she was started on subcutaneous adalimumab injection monthly, three and a half years prior to her initial visit.

Keyword

Adalimumab; Psoriasiform eruption

MeSH Terms

Antibodies, Monoclonal, Humanized
Arthritis, Rheumatoid
Crohn Disease
Dermatitis
Female
Humans
Lower Extremity
Psoriasis
Skin
Spondylitis, Ankylosing
Tumor Necrosis Factor-alpha
Adalimumab
Antibodies, Monoclonal, Humanized
Tumor Necrosis Factor-alpha
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