Korean J Dermatol.  2015 Sep;53(8):635-637.

A Case of Squamous Cell Carcinoma Originating from Oral Lichen Planus

• Kim BR
• Byun SY
• Chung JH
• Cho KH

Abstract

Oral lichen planus (OLP) is a relatively common chronic inflammatory disease of uncertain etiology. OLP lesions rarely undergo spontaneous remission and have the potential to undergo malignant transformation. The risk of malignant transformation in OLP is estimated to be between 0.4% and 5.3%; two clinical studies in Korea reported the frequency of malignant change as 2.9% and 2.85%. However, to the best of our knowledge, there has been no individual case report in the Korean dermatological literature to date regarding the malignant transformation of OLP. Herein, we report the case of a 77-year-old Korean woman with long-standing OLP that underwent transformation to oral squamous cell carcinoma. This is the first well-documented case report of squamous cell carcinoma that developed from OLP.

Keyword

Biopsy; Lichen planus; Malignant transformation; Oral lichen planus; Squamous cell carcinoma

MeSH Terms

Aged
Biopsy
Carcinoma, Squamous Cell*
Female
Humans
Korea
Lichen Planus
Lichen Planus, Oral*
Remission, Spontaneous