J Gynecol Oncol.  2012 Jul;23(3):205-206. 10.3802/jgo.2012.23.3.205.

Unusual involvement of cervix and vulva in a case of chronic lymphocytic leukemia

Affiliations
  • 1Department of Medical Oncology, Cancer Institute (WIA), Adyar, India. pg1980@gmail.com
  • 2Department of Pathology, Cancer Institute (WIA), Adyar, India.

Abstract

No abstract available.


MeSH Terms

Cervix Uteri
Female
Leukemia, Lymphocytic, Chronic, B-Cell
Vulva

Figure

  • Fig. 1 (A) Swelling and ulcerative lesion over inner surface of both labia majora. (B) Labial biopsy showed sheets of mature appearing lymphocytes (H&E, ×100). (C) Immunohistochemistry (IHC) showing CD 5 positivity of mature lymphocyte (×100). (D) Post chemotherapy response showing significant decrease in vulval swelling and ulcerative lesion. (E) IHC showing CD 43 positivity of mature lymphocyte (×100). (F) Endocervical smear also many mature appearing lymphoid cells and few squamous cell (H&E, ×100).


Reference

1. Epstein E, MacEachern K. Dermatologic manifestations of the lymphoblastoma-leukemia group. Arch Intern Med. 1937. 60:867–875.
2. Vang R, Medeiros LJ, Silva EG, Gershenson DM, Deavers M. Non-Hodgkin's lymphoma involving the vagina: a clinicopathologic analysis of 14 patients. Am J Surg Pathol. 2000. 24:719–725.
3. Katsnelson M, Laughingwell R, Rose LJ, Rosenblum NG. Colposcopic and cytologic detection of chronic lymphocytic leukemia in the vagina: a case report. J Reprod Med. 2011. 56:344–346.
4. Mikhail MS, Runowicz CD, Kadish AS, Romney SL. Colposcopic and cytologic detection of chronic lymphocytic leukemia. Gynecol Oncol. 1989. 34:106–108.
5. Vang R, Medeiros LJ, Ha CS, Deavers M. Non-Hodgkin's lymphomas involving the uterus: a clinicopathologic analysis of 26 cases. Mod Pathol. 2000. 13:19–28.
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