Korean J Gynecol Oncol.  2007 Jun;18(2):160-164.

Malignant lymphoma of the uterine cervix treated by neoadjuvant chemotherapy

• Hwang SH
• Kim BY
• Park JH
• Lee KE
• Lee MA
• Lee KH
• Noh HT
• Son SK

Abstract

Non-Hodgkin's lymphoma presented as a malignancy of the uterine cervix is exceedingly rare disease and accounts for approximately only 0.12-0.6% of extranodal lymphomas. There is no consensus on the management and prognosis of the disease because of its extreme rarity. Previously, treatment of this disease has been radiation therapy, surgery or chemotherapy either alone or in combination. We present the case of a 45-year-old woman diagnosed with diffuse, large B-cell non-Hodgkin's lymphoma of the uterine cervix. We administered neoadjuvant chemotherapy according to CHOP protocol (cyclophosphamide, adriamycin, vincristine, and prednisone) followed by hysterectomy and bilateral salpingo-oophorectomy. The patient is alive 20 months after the initial diagnosis. We report the case with a brief review of literature.

Keyword

Lymphoma; Cervical lymphoma; Neoadjuvant chemotherapy

MeSH Terms

B-Lymphocytes
Cervix Uteri*
Consensus
Diagnosis
Doxorubicin
Drug Therapy*
Female
Humans
Hysterectomy
Lymphoma*
Lymphoma, Non-Hodgkin
Middle Aged
Prognosis
Rare Diseases
Vincristine
Doxorubicin
Vincristine