Korean J Med Phys.  2010 Mar;21(1):16-21.

Comparison of Radioactivity Measurement with Radionuclide Calibrators in Nuclear Medicine Centers

• Son HK
• Kim JH
• Lim C
• Yang HK
• Park KJ
• Oh HJ
• Kim HJ
• Kim DS

Abstract

To acquire good image quality and to minimize unnecessary radiation dose to patients, it is important to ensure that the radiopharmaceutical administered is accurately measured. Quality control of radionuclide calibrators should be performed to achieve these goals. The purpose of this study is to support the quality control of radionuclide calibrators in nuclear medicine centers and to investigate the level of measurement accuracy of the radionuclide calibrators. 58 radionuclide calibrators from 45 nuclear medicine centers, 74 radionuclide calibrators from 58 nuclear medicine centers, and 60 radionuclide calibrators from 45 nuclear medicine centers were tested with I-131, Tc-99m and I-123, respectively. The results showed that 81% of calibrators for I-131, 61% of calibrators for Tc-99m and 67% of calibrators for I-123 were within +/-5%. 17% of calibrators for I-131, 20% of calibrators for Tc-99m and 15% of calibrators for I-123 had a deviation in the range 5%<|delta|< or =10%. 2% of calibrators for I-131, 19% of calibrators for Tc-99m and 18% of calibrators for I-123 had a deviation of |delta|>10%. Follow-up measurements were performed on the calibrators whose error exceeded the +/-10% limit. As a result, some of the calibrator showed an improvement and their deviation decreased below the +/-10% limit. The results have shown that such comparisons are necessary to improve the accuracy of the measurement and to identify malfunctioning radionuclide calibrators.

Keyword

Comparison of radioactivity measurement; Radionuclide calibrator; I-131; Tc-99m; I-123

MeSH Terms

Dietary Sucrose
Follow-Up Studies
Humans
Nuclear Medicine
Quality Control
Radioactivity
Dietary Sucrose