Korean J Anesthesiol.  1989 Apr;22(2):211-217. 10.4097/kjae.1989.22.2.211.

Effects of IPV ( Intrapulmonary Percussive Ventilation ) on Cardiopulmonary Hemodynamics and Oxygenation in Dogs

Affiliations
  • 1Department of Anesthesiology, College of Medicine, Seoul National University, Seoul, Korea.

Abstract

To evaluate effects of IPV (Intrapulmonary Percussive Ventilation) on cardiopulmonary hemodynamics and oxygenation, we compared IPV with conventional IPPV (Intermittent Positive Pressure Ventilation} in eight mongrel dogs. After Swan-Ganz catheterization and femoral arterial cannulation, we applied IPPU and IPV for 30 minutes respectively at random order. There were no significant differences in cardiac output (CO), heart rate (HR), mean arterial pressure (MAP), vascular resistance (VR), pulmonary capillary wedge pressure (PCWP), rate pressure product (RPP), coronary perfusion pressure (CPP) and oxygenation-reflecting parameters such as AaDO2, oxygen flux and oxygen consumption (VO2) between IPPV and IPV. A slight increase of diastolic pulmonary arterial pressure (PAP) resulted in increase of pulmonary perfusion pressure (PPP). IPV increases left and right ventricular stroke work index which might be related to slight metabolic acidosis and a little deficient ventilation during IPV. We can conclude that IPV is safe and good in cardiopulmonary hemodynamics and tissue oxygena-tion in dogs, but its better to be cautious in ventilation during IPV.

Keyword

IPV; Hemodynamics; Oxygenation; Dogs

MeSH Terms

Acidosis
Animals
Arterial Pressure
Cardiac Output
Catheterization
Catheterization, Swan-Ganz
Dogs*
Heart Rate
Hemodynamics*
Intermittent Positive-Pressure Ventilation
Oxygen Consumption
Oxygen*
Perfusion
Pulmonary Wedge Pressure
Stroke
Vascular Resistance
Ventilation*
Oxygen
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