The Effects of Liquid Na-heparin and Dry Li-heparin on arterial blood gas analysis, hemoglobin and electrolyte measurement

Kim, Chi Hyo; Kim, Jong Hak; Chae, Wha Joo; Lee, Choon Hi

Abstract

Arterial blood gas analysis is essential laboratory test in monitoring of acid-base balance and respiratory care, but it has been known that there was many variabilities according to method of sampling and care before analysis. We compared the effects of liquid Na heparin and dry Li-heparin on blood gas analysis, hemoglobin and electrolytes, and studied in 25 patients who were taken elective operation with radial arterial eannulation. The samples were obtained from radial artery; sample 1, drawn to a total volume of 1 cc with 2cc plastic syringe utilizing liquid Na-heparin; sample 2, drawn to a total volume of 2 cc with 2 cc plastic syringe utilizing liquid Na-heparin ; sample 3, drawn to a total volume of 1 cc with Bard parker Preset 1 cc kit that pre-filled dry Li-heparin; control value, sampled arterial blood without heparin for measurement of hemoglobin and electrolytes. These samples were analyzed with minimum error, as possible. We obtained the following results. 1) There was no atatistical difference in pH, PCO2, PO2 and hemoglobin in each sample. 2) The value of Na+ and K+ were no statistical differences in sample 1,2 and 3, but sig- nificantly lower level than control value (P<0.01). 3) The Ca2+ level was significantly lower in sample 1 and 2(P<0.01) and not significantly different in sample 3 when compared with the control value. The Ca level was significantly higher in sample 2 and 3 when compared with sample 1 (P<0.01). So we conclude that arterial blood gas analysis and hemoglobin level showed no statistical difference between the liquid Na heparin and the dry Li-heparin. Heparin is not suitable for Na+ and K+ measurement. Low dose liquid Na heparin and dry Li heparin is reliable for obtaining Ca2+ level.