Korean J Anesthesiol.  1991 Feb;24(1):188-193. 10.4097/kjae.1991.24.1.188.

Clinical Evaluation of Anesthetic Management for Pheochromocytoma Following Prazosin Pre-treament

• Koo JS
• Kwon HK
• Cho OH

• KMID: 2239389
• DOI: http://doi.org/10.4097/kjae.1991.24.1.188

Abstract

Perioperative management of patients with pheochromocytoma is challenging. Accordingly, proper preoperative preparation is important. Prazosin, a selective alpha I blocker, may offer a potential advantage. This 54-year-old woman was treated with prazosin 2 mg, b.i.d. for 15 days and also with propranolol 20 mg, b.i.d. for a few days intermittently before the proposed surgery. Both symptoms and blood pressure were well controlled effectively. Induction of anesthesia was accomplished with nitrolingual spray, fentanyl 100 ug, 1% idocaine 50 mg, 2.5% thiopental sodium 200 mg, vecuronium 6 mg and 100% O2-enflurane. During the surgical and anesthetic procedure, the patient showed a reduced incidence of excessive blood-pressure variations and no arrhythmia was present except for supraventricular ectopic beats. Conclusively, we believe that careful preoperative preparation is recommended to minimize intraoperative hemodynamic dieturbances and their sequelae.

Keyword

Pheochromocytoma; Preoperative preparation; Prazosin

MeSH Terms

Anesthesia
Arrhythmias, Cardiac
Blood Pressure
Female
Fentanyl
Hemodynamics
Humans
Incidence
Middle Aged
Pheochromocytoma*
Prazosin*
Propranolol
Thiopental
Vecuronium Bromide
Fentanyl
Prazosin
Propranolol
Thiopental
Vecuronium Bromide