Korean J Anesthesiol.  1991 Feb;24(1):37-42. 10.4097/kjae.1991.24.1.37.

Changes in Serum Electrolyte Concentration after Induction of Anesthesia with Intravenous Anesthetics and Nondepolarizing Muscle Relaxant

• Kim MJ
• Park DP

• KMID: 2239366
• DOI: http://doi.org/10.4097/kjae.1991.24.1.37

Abstract

The aim of this study was to compare the changes of serum electrolyte concentration during the peri-induction period of anesthesia with depolarizing muscle relaxant or nondepolarizing muscle relaxant for endotracheal intubation. The study population was from 60 patients scheduled for elective surgery at Yeungnam University Hospital, who belonged to physical status I or II of ASA classification. Patients were divided into 2 groups; a) succinylcholine administered grouy (control group, Group A), b) vecuronium administered group (study group, Group B). The results were as follows; 1) The serum potassium concentration was significantly increased (p<0.05) in 5 minute post-induction compared with pre-induction in control group, but significantly decreased (p<0.05) in study group.2) The serum sodium and chloride concentrations were slightly deceased in 5 minute post-induction compared with pre-induction in both control and study groups, but no statistical significance was noticed in both groups. It is concluded that intravenous administration of nondepolarizing muscle relaxant (Vecuronium) for endotracheal intubation is safer than depolarizing muscle relaxanf (Succinylcholine) in the critical hyperkalemia conditions such as burn, multiple trauma, spinal cord injury, neuromuscular disease and uremia.

Keyword

Vecuronium; Succinylcholine; Hyperkalemia

MeSH Terms

Administration, Intravenous
Anesthesia*
Anesthetics, Intravenous*
Burns
Classification
Humans
Hyperkalemia
Intubation, Intratracheal
Multiple Trauma
Neuromuscular Diseases
Potassium
Sodium
Spinal Cord Injuries
Succinylcholine
Uremia
Vecuronium Bromide
Anesthetics, Intravenous
Potassium
Sodium
Succinylcholine
Vecuronium Bromide