Korean J Anesthesiol.  1991 Jun;24(3):510-514. 10.4097/kjae.1991.24.3.510.

The Effects of the Small Doses of Nondepolarzing Muscle Relaxants Administered Just Prior to Succinylcholine on Intragastric and Intraocular Pressures

• Lee SC
• Lee SM
• Choe IH
• Ham BM

• KMID: 2239277
• DOI: http://doi.org/10.4097/kjae.1991.24.3.510

Abstract

Succinylcho1ine(Sch) may provoke regurgitation of gastric contents by producing fasciculations of abdominal musculatrue, which in turn may increase intragastric pressure. And it has been also believed that Sch increases intraocular pressure in part by contracture of the extraocular muscles. The purpose of this study was to determine whether these increases and the degree of fasciculation could be reduced by prior administration of a nondepolarizing muscle relaxant. Simultaneous administration of pancuronium or vecuronium with Sch significantly reduced the degree of fasciculation and also decreased the elevation of the intragastric pressure, but did not show any remarkable effect on the intraocular pressure, We might say that wed better use the small amount of nondepolarizing muscle relaxant with Sch to prevent the increase of intragastric pressure, thereby decrease the chance of regurgitation and aspiration during induction period.

Keyword

Succinylcholine; Nondepolarizing muscle relaxant; Intragastric pressure; Fascieulation; Intraocular pressure

MeSH Terms

Contracture
Fasciculation
Intraocular Pressure*
Muscles
Pancuronium
Succinylcholine*
Vecuronium Bromide
Pancuronium
Succinylcholine
Vecuronium Bromide