Korean J Anesthesiol.  1993 Apr;26(2):293-298. 10.4097/kjae.1993.26.2.293.

Cardiovascular Effect of Lidocaine in Patients under Halothane , Enflurane and Diazepam Anesthesia

• Shin BH
• Gwak SH
• Chung SS
• Ha IH

• KMID: 2239257
• DOI: http://doi.org/10.4097/kjae.1993.26.2.293

Abstract

To evaluate the cardiovascular effect of lidocaine and serum electrolytes during inhalational or intravenous anesthesia, thirty-two healthy patients were randomly divided into three groups and measured systolic pressure, diastolic pressure, mean pressure, heart rate and serum K+ and Na+ level were measured at 30 sec, l, 3, 6, 12 minutes after intravenous injection of lidocaine(1.5 mg/kg) during halothane-N2O-O2 or enflurane-N2O-O2 or diazepam-N2O-O2 anesthesia. In all 3 groups, the values of hemodynamic and serum electrolytes were not changed by 2% lidocaine. These results indicate that intravenous injection of lidocaine(1.5 mg/kg) to prevent undesirable reflexes and to prevent intracranial hypertension is a safe method without depression of hemodynamics.

Keyword

Anesthetics; halothane; enflurane; diazepam; local Anesthetics; lidocaine; Cardiovascular effect

MeSH Terms

Anesthesia*
Anesthesia, Intravenous
Anesthetics
Anesthetics, Local
Blood Pressure
Depression
Diazepam*
Electrolytes
Enflurane*
Halothane*
Heart Rate
Hemodynamics
Humans
Injections, Intravenous
Intracranial Hypertension
Lidocaine*
Reflex
Anesthetics
Anesthetics, Local
Diazepam
Electrolytes
Enflurane
Halothane
Lidocaine