The Effects of Preloading Solution on Blood Glucose Levels of Newborn Baby during Epidural Anesthesia for Cesarean Section

Lim, Hae Ja; Kim, Sun Hee; Lee, Hye Won; Chae, Byoung Kuk; Shin, Jung Soon; Chang, Seong Ho

Abstract

It is common for patient undergoing cesarean section under epidural anesthesia to have lower blood pressure because of not only supine hypotension syndrome but vasodilation due to sympathetic blockade. So it is necessary to give large volume of fluid before perfarming epidural anesthesia to prevent hypotension. When we use the dextrose containing fluid for that purpose, newborn baby could have a high blood glucose at delivery and low blood glucose level due to high insulin level after birth. The authors examined the blood glucose level at delivery and two hours after birth following use of 5% dextrose in lactated Ringers solution(HD group, n=24) or lactated Ringers solution (HS group, n=24) for prevention of hypotension during epidural anesthesia for cesarean section The results were as follows; I) The total amount of fluid was 789.6+/-264.2 ml in HD group and 741.1+/-253.5 ml in HS group. 2) The glucose level of mother at delivery was 300.9+/-76.3 mg/dl in HD group and 98.7+/-24.6 mg/dl in HS group and there was statistical significance(p< 0.01). 3) In HD group, the glucose level of newborn baby was 212.2+/-57.2 mg/dl at delivery and 465.+/-20.3 mg/dl at 2 hours after birth. The change of amount during 2 hours after birth was highly related to the glucose level at birth. Higher level of glucose at birth, larger amount of change during 2 hours after birth. 4) In HS group, the glucose level of newborn baby was 66.8+/-10.2 mg/dl at birth and 67.0+/-12.1 mg/dl at 2 hours after birth. There was no significant change.