Korean J Anesthesiol.  1998 Feb;34(2):308-314. 10.4097/kjae.1998.34.2.308.

Power Spectral Components Analysis of Heart Rate Variability during Propofol-O2-N2O Anesthesia

Affiliations
  • 1Department of Anesthesiology, Samsung Medical Center, Seoul, Korea.
  • 2Department of Anesthesiology, College of Medicine, Seoul National University, Seoul, Korea.

Abstract

BACKGROUND
Beat-to-beat heart rate variability (HRV) is caused by the fluctuating balance of sympathetic and parasympathetic tone. Analysis of heart rate variations may provide important clinical information and the influence of anesthesia on the autonomic nervous system.
METHODS
We studied 18 ASA I female patients undergoing propofol-O2-N2O anesthesia for transabdominal hysterectomy and analyzed the HRV using power spectral analysis (PSA) at preinduction period, 2~5 minutes after induction, and 30~33 minutes after skin incision.
RESULTS
The powers in all frequency bands decreased, but the decrease in low+middle frequency power was less than that in high frequency power during 2~5 minutes after induction. At 30~33 minutes after skin incision, all frequency bands and ratio of low middle/high frequency power spectra recovered and were not significantly different from those of before induction.
CONCLUSIONS
Propofol-N2O-O2 anesthesia depress autonomic nervous system with relative preservation of sympathetic components. However autonomic nervous system and sympathetic/parasympathetic balance during operation recovered to the pre-anesthetic pattern, probably due to surgical stimuli and stress.

Keyword

Anesthetics; Intravenous: propofol; Heart: heart rate variability; Power spectral analysis

MeSH Terms

Anesthesia*
Anesthetics
Autonomic Nervous System
Female
Heart Rate*
Heart*
Humans
Hysterectomy
Skin
Anesthetics
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