Korean J Anesthesiol.  2002 Apr;42(4):493-499. 10.4097/kjae.2002.42.4.493.

Two or Three Times of Short Deep Hypothermic Circulatory Arrest (DHCA)within 20 Minutes, Total Not Exceeding 60 Minutes, Does Not Impair Brain Function in Adults

• Kim TS
• Oh MS
• Choi KM

• KMID: 2236785
• DOI: http://doi.org/10.4097/kjae.2002.42.4.493

Abstract

BACKGROUND: Deep Hypothermic circulatory Arrest (DHCA) is widely used during heart surgery in neonates and infants and complicated surgeries in adults such as a pulmonary thromboendarterectomy (PTE). However safe limits of time and temperature during DHCA still remain controversial. Futhermore it's effects on neurologic outcome has been controversial.
METHODS
On the postoperative 3 days, we examined the neurologic function of 12 patients who received a PTE. During the PTE, DHCA was done 2 or 3 times within 20 minutes. Between DHCAs the patients were perfused at a low flow rate with 18degreesC blood until their venous saturation returned to 90%. Neurologic evaluations included level of consciousness, Glasgow coma scale (GCS), and motor and sensory functions.
RESULTS
Neurologic functions of all of the patients assessed on the 3 days postoperatively was grossly normal. All 12 patients were oriented to time, place, and person with normal gross motor and sensory functions.
CONCLUSIONS
No significant neurologic complications were related to the technique of two or three times of short DHCA within 20 minutes, for a total not exceeding 60 minutes.

Keyword

Brain protection; circulatory arrest; neurologic complication; pumonary thromboendarterectomy

MeSH Terms

Adult*
Brain*
Circulatory Arrest, Deep Hypothermia Induced*
Consciousness
Endarterectomy
Glasgow Coma Scale
Humans
Infant
Infant, Newborn
Sensation
Thoracic Surgery