Korean J Anesthesiol.  2007 Oct;53(4):528-531. 10.4097/kjae.2007.53.4.528.

Amiodarone Induced Toxic Hepatitis: A case report

• Kim SJ
• Koo BW
• Bae JH
• Lim SW

• KMID: 2236606
• DOI: http://doi.org/10.4097/kjae.2007.53.4.528

Abstract

Although amiodarone is a widely used and effective long-term antiarrhythmic drug, it is known to have life-threatening adverse effects, including acute hepatotoxicity. Although the occurrence of acute hepatotoxicity after amiodarone administration is rare, it can be fatal. However, this phenomenon has not been well studied. Here, we describe a 39 year old woman with atrial fibrillation and supraventricular tachycardia who developed acute toxic hepatitis within 8 days of amiodarone administration at the recommended dosage. The drug was withdrawn and the laboratory findings progressively returned to normal.

Keyword

amiodarone; cardiac arrhythmia; hepatotoxicity

MeSH Terms

Adult
Amiodarone*
Arrhythmias, Cardiac
Atrial Fibrillation
Drug-Induced Liver Injury*
Female
Humans
Tachycardia, Supraventricular
Amiodarone