Int Neurourol J.
2013 Sep;17(3):107-113.
Exposure to Music and Noise During Pregnancy Influences Neurogenesis and Thickness in Motor and Somatosensory Cortex of Rat Pups
- Affiliations
-
- 1Department of Urology, Gachon University Gil Medical Center, Gachon University, Incheon, Korea. kimcho99@gilhospital.com
- 2Department of Urology, Gachon University of Medicine and Science, Incheon, Korea.
- 3Department of Physiology, Kyung Hee University School of Medicine, Seoul, Korea.
- 4Department of Psychiatry, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea.
- 5Department of Physical Therapy, Kyungnam University, Changwon, Korea.
Abstract
- PURPOSE
Prenatal environmental conditions affect the development of the fetus. In the present study, we investigated the effects of exposure to music and noise during pregnancy on neurogenesis and thickness in the motor and somatosensory cortex of rat pups.
METHODS
The pregnant rats in the music-applied group were exposed to 65 dB of comfortable music for 1 hour, once per day, from the 15th day of pregnancy until delivery. The pregnant rats in the noise-applied group were exposed to 95 dB of sound from a supersonic sound machine for 1 hour, once per day, from the 15th day of pregnancy until delivery. After birth, the offspring were left undisturbed together with their mother. The rat pups were sacrificed at 21 days after birth.
RESULTS
Exposure to music during pregnancy increased neurogenesis in the motor and somatosensory cortex of rat pups. In contrast, rat pups exposed to noise during pregnancy showed decreased neurogenesis and thickness in the motor and somatosensory cortex.
CONCLUSIONS
Our study suggests that music and noise during the developmental period are important factors influencing brain development and urogenital disorders.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Compensatory Hyperactivity of the Ipsilesional Red Nucleus in a Patient With Somatosensory Cortex Damage: A Case Report
- Immunohistochemical Study on the Changes of Neuropeptide Y Immunoreactive Neurons in the Corpus Striatum and Motor System of Aged Rat
- Morphologic Changes of Lung Parenchymal Tissue in Neonatal Rat Pups Under Chronic Hyperoxia
- Change of Subjective Tinnitus by the Duration of Noise Exposure in Patients with Noise-Induced Hearing Loss
- Measurement of Acceptable Noise Level with Background Music
