Korean J Dermatol.  1999 Sep;37(9):1343-1347.

A Case of Peripheral T-cell Lymphoma Manifesting Bilateral Periobital Infiltration with Swelling

• Yoon YM
• Jang HC
• Kim DS
• Kim SW

Abstract

Periorbital swelling is a rather common symptom. Of the causes, the associated lymphoproliferative diseases rarely involve, and, if any, pseudolymphoma and B-cell type of lymphoma are mostly implicated. We report herein a case of unspecified peripheral T-cell lymphoma presenting as only manifestation of bilateral orbital swelling. A 32-year-old woman had a fluctuant course of bilateral mild erythematous swelling without ocular or lymph node involvement for about 2 years. Biopsy specimens from the left upper eyelid showed infiltration of medium-sized atypical cells with pleomorphism, convoluted nuclei, scant cytoplasm and less prominent nuclei. The cell was LCA, UCHL-1 and CD3 positive, but negative for L26. She received six cycles of CHOP combined therapy, with a marked improvement. No relapse was noted during a period of about a 6-month follow-up.

Keyword

Peripheral T-cell lymphoma; Periorbital swelling

MeSH Terms

Adult
B-Lymphocytes
Biopsy
Cytoplasm
Eyelids
Female
Follow-Up Studies
Humans
Lymph Nodes
Lymphoma
Lymphoma, T-Cell, Peripheral*
Orbit
Pseudolymphoma
Recurrence